HDAC6 inhibition by tubastatin A is protective against oxidative stress in a photoreceptor cell line and restores visual function in a zebrafish model of inherited blindness

Retinal diseases, such as hereditary retinitis pigmentosa and age-related macular degeneration, are characterized by the progressive loss of photoreceptors. Histone deacetylase 6 (HDAC6) is considered as a stress surveillance factor and a potential target for neuroprotection and regeneration. Overex...

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Detalles Bibliográficos
Autores principales: Leyk, Janina, Daly, Conor, Janssen-Bienhold, Ulrike, Kennedy, Breandán N, Richter-Landsberg, Christiane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5596594/
https://www.ncbi.nlm.nih.gov/pubmed/29048427
http://dx.doi.org/10.1038/cddis.2017.415

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5596594/
https://www.ncbi.nlm.nih.gov/pubmed/29048427
http://dx.doi.org/10.1038/cddis.2017.415

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