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Lysosomotropism depends on glucose: a chloroquine resistance mechanism

There has been long-standing interest in targeting pro-survival autophagy as a combinational cancer therapeutic strategy. Clinical trials are in progress testing chloroquine (CQ) or its derivatives in combination with chemo- or radiotherapy for solid and haematological cancers. Although CQ has shown...

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Detalles Bibliográficos
Autores principales:	Gallagher, Laura E, Radhi, Ohood A, Abdullah, Mahmud O, McCluskey, Anthony G, Boyd, Marie, Chan, Edmond Y W
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2017
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5596595/ https://www.ncbi.nlm.nih.gov/pubmed/28837152 http://dx.doi.org/10.1038/cddis.2017.416

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