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The aberrant upstream pathway regulations of CDK1 protein were implicated in the proliferation and apoptosis of ovarian cancer cells

BACKGROUND: Upregulation of Cyclin dependent kinase 1 (CDK1) protein is closely related with the prognosis of several malignant tumors. Chk1-CDC25C-CDK1 signaling and P53-P21WAF1-CDK1 signaling pathways are closely related with the cell cycle G2/M phase regulation. The present study aimed to analyze...

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Detalles Bibliográficos
Autores principales: Zhang, Ruitao, Shi, Huirong, Ren, Fang, Zhang, Minghui, Ji, Pengcheng, Wang, Wenwen, Liu, Chuanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5596843/
https://www.ncbi.nlm.nih.gov/pubmed/28899430
http://dx.doi.org/10.1186/s13048-017-0356-x