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Serotonin augmentation therapy by escitalopram has minimal effects on amyloid-β levels in early-stage Alzheimer’s-like disease in mice

BACKGROUND: Dysfunction of the serotonergic (5-HTergic) system has been implicated in the cognitive and behavioural symptoms of Alzheimer’s disease (AD). Accumulation of toxic amyloid-β (Aβ) species is a hallmark of AD and an instigator of pathology. Serotonin (5-HT) augmentation therapy by treatmen...

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Detalles Bibliográficos
Autores principales:	von Linstow, Christian Ulrich, Waider, Jonas, Grebing, Manuela, Metaxas, Athanasios, Lesch, Klaus Peter, Finsen, Bente
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5596844/ https://www.ncbi.nlm.nih.gov/pubmed/28899417 http://dx.doi.org/10.1186/s13195-017-0298-y

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