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Increased plasma lipid levels exacerbate muscle pathology in the mdx mouse model of Duchenne muscular dystrophy

BACKGROUND: Duchenne muscular dystrophy (DMD) is caused by loss of dystrophin expression and leads to severe ambulatory and cardiac function decline. However, the dystrophin-deficient mdx murine model of DMD only develops a very mild form of the disease. Our group and others have shown vascular abno...

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Detalles Bibliográficos
Autores principales: Milad, Nadia, White, Zoe, Tehrani, Arash Y., Sellers, Stephanie, Rossi, Fabio M.V., Bernatchez, Pascal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5596936/
https://www.ncbi.nlm.nih.gov/pubmed/28899419
http://dx.doi.org/10.1186/s13395-017-0135-9