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Regulatory network changes between cell lines and their tissues of origin

BACKGROUND: Cell lines are an indispensable tool in biomedical research and often used as surrogates for tissues. Although there are recognized important cellular and transcriptomic differences between cell lines and tissues, a systematic overview of the differences between the regulatory processes...

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Detalles Bibliográficos
Autores principales:	Lopes-Ramos, Camila M., Paulson, Joseph N., Chen, Cho-Yi, Kuijjer, Marieke L., Fagny, Maud, Platig, John, Sonawane, Abhijeet R., DeMeo, Dawn L., Quackenbush, John, Glass, Kimberly
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5596945/ https://www.ncbi.nlm.nih.gov/pubmed/28899340 http://dx.doi.org/10.1186/s12864-017-4111-x

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