Kinetic and thermodynamic studies reveal chemokine homologues CC11 and CC24 with an almost identical tertiary structure have different folding pathways

BACKGROUND: Proteins with low sequence identity but almost identical tertiary structure and function have been valuable to uncover the relationship between sequence, tertiary structure, folding mechanism and functions. Two homologous chemokines, CCL11 and CCL24, with low sequence identity but simila...

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Detalles Bibliográficos
Autores principales: Ge, Baosheng, Jiang, Xiaoyong, Chen, Yao, Sun, Tingting, Yang, Qiuxia, Huang, Fang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5596964/
https://www.ncbi.nlm.nih.gov/pubmed/28919974
http://dx.doi.org/10.1186/s13628-017-0039-4

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