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Epigenetic regulation of metalloproteinases and their inhibitors in rotator cuff tears

Rotator cuff tear is a common orthopedic condition. Metalloproteinases (MMP) and their inhibitors (TIMP) seem to play a role in the development of joint injuries and in the failure of tissue healing. However, the mechanisms of regulation of gene expression in tendons are still unknown. Epigenetic me...

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Detalles Bibliográficos
Autores principales: Leal, Mariana Ferreira, Caires dos Santos, Leonardo, Martins de Oliveira, Adrielle, Santoro Belangero, Paulo, Antônio Figueiredo, Eduardo, Cohen, Carina, de Seixas Alves, Felipe, Hiromi Yanaguizawa, Wânia, Vicente Andreoli, Carlos, de Castro Pochini, Alberto, Ejnisman, Benno, Cardoso Smith, Marília, de Seixas Alves, Maria Teresa, Cohen, Moises
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5597200/
https://www.ncbi.nlm.nih.gov/pubmed/28902861
http://dx.doi.org/10.1371/journal.pone.0184141