The cytoprotective protein clusterin is overexpressed in hypergastrinemic rodent models of oxyntic preneoplasia and promotes gastric cancer cell survival

The cytoprotective protein clusterin is often dysregulated during tumorigenesis, and in the stomach, upregulation of clusterin marks emergence of the oxyntic atrophy (loss of acid-producing parietal cells)-associated spasmolytic polypeptide-expressing metaplasia (SPEM). The hormone gastrin is import...

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Detalles Bibliográficos
Autores principales: Vange, Pål, Bruland, Torunn, Doseth, Berit, Fossmark, Reidar, Sousa, Mirta M. L., Beisvag, Vidar, Sørdal, Øystein, Qvigstad, Gunnar, Waldum, Helge L., Sandvik, Arne K., Bakke, Ingunn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5597207/
https://www.ncbi.nlm.nih.gov/pubmed/28902909
http://dx.doi.org/10.1371/journal.pone.0184514

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