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Purification of Monoclonal Antibodies Using a Fiber Based Cation-Exchange Stationary Phase: Parameter Determination and Modeling
Monoclonal antibodies (mAb) currently dominate the market for protein therapeutics. Because chromatography unit operations are critical for the purification of therapeutic proteins, the process integration of novel chromatographic stationary phases, driven by the demand for more economic process sch...
Autores principales: | Schwellenbach, Jan, Zobel, Steffen, Taft, Florian, Villain, Louis, Strube, Jochen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5597267/ https://www.ncbi.nlm.nih.gov/pubmed/28952586 http://dx.doi.org/10.3390/bioengineering3040024 |
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