Cargando…
Dynein efficiently navigates the dendritic cytoskeleton to drive the retrograde trafficking of BDNF/TrkB signaling endosomes
The efficient transport of cargoes within axons and dendrites is critical for neuronal function. Although we have a basic understanding of axonal transport, much less is known about transport in dendrites. We used an optogenetic approach to recruit motor proteins to cargo in real time within axons o...
Autores principales: | Ayloo, Swathi, Guedes-Dias, Pedro, Ghiretti, Amy E., Holzbaur, Erika L. F. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5597326/ https://www.ncbi.nlm.nih.gov/pubmed/28720664 http://dx.doi.org/10.1091/mbc.E17-01-0068 |
Ejemplares similares
-
Dynein activator Hook1 is required for trafficking of BDNF-signaling endosomes in neurons
por: Olenick, Mara A., et al.
Publicado: (2019) -
SORLA-Mediated Trafficking of TrkB Enhances the Response of Neurons to BDNF
por: Rohe, Michael, et al.
Publicado: (2013) -
A neuron-specific cytoplasmic dynein isoform preferentially transports TrkB signaling endosomes
por: Ha, Junghoon, et al.
Publicado: (2008) -
Retrograde BDNF to TrkB signaling promotes synapse elimination in the developing cerebellum
por: Choo, Myeongjeong, et al.
Publicado: (2017) -
Retrolinkin cooperates with endophilin A1 to mediate BDNF–TrkB early endocytic trafficking and signaling from early endosomes
por: Fu, Xiuping, et al.
Publicado: (2011)