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The θ‐defensin retrocyclin 101 inhibits TLR4‐ and TLR2‐dependent signaling and protects mice against influenza infection

Despite widespread use of annual influenza vaccines, seasonal influenza‐associated deaths number in the thousands each year, in part because of exacerbating bacterial superinfections. Therefore, discovering additional therapeutic options would be a valuable aid to public health. Recently, TLR4 inhib...

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Detalles Bibliográficos
Autores principales: Prantner, Daniel, Shirey, Kari Ann, Lai, Wendy, Lu, Wuyuan, Cole, Alexander M., Vogel, Stefanie N., Garzino‐Demo, Alfredo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Leukocyte Biology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5597516/
https://www.ncbi.nlm.nih.gov/pubmed/28729359
http://dx.doi.org/10.1189/jlb.2A1215-567RR