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Identification of stiffness-induced signalling mechanisms in cells from patent and fused sutures associated with craniosynostosis

Craniosynostosis is a bone developmental disease where premature ossification of the cranial sutures occurs leading to fused sutures. While biomechanical forces have been implicated in craniosynostosis, evidence of the effect of microenvironmental stiffness changes in the osteogenic commitment of ce...

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Detalles Bibliográficos
Autores principales: Barreto, Sara, González-Vázquez, Arlyng, R. Cameron, Andrew, O’Brien, Fergal J., Murray, Dylan J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5597583/
https://www.ncbi.nlm.nih.gov/pubmed/28904366
http://dx.doi.org/10.1038/s41598-017-11801-0