Vδ2+ T cell response to malaria correlates with protection from infection but is attenuated with repeated exposure

Vδ2(+) γδ T cells are semi-innate T cells that expand markedly following P. falciparum (Pf) infection in naïve adults, but are lost and become dysfunctional among children repeatedly exposed to malaria. The role of these cells in mediating clinical immunity (i.e. protection against symptoms) to mala...

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Detalles Bibliográficos
Autores principales: Jagannathan, Prasanna, Lutwama, Fredrick, Boyle, Michelle J., Nankya, Felistas, Farrington, Lila A., McIntyre, Tara I., Bowen, Katherine, Naluwu, Kate, Nalubega, Mayimuna, Musinguzi, Kenneth, Sikyomu, Esther, Budker, Rachel, Katureebe, Agaba, Rek, John, Greenhouse, Bryan, Dorsey, Grant, Kamya, Moses R., Feeney, Margaret E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5597587/
https://www.ncbi.nlm.nih.gov/pubmed/28904345
http://dx.doi.org/10.1038/s41598-017-10624-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5597587/
https://www.ncbi.nlm.nih.gov/pubmed/28904345
http://dx.doi.org/10.1038/s41598-017-10624-3

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