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Syk-dependent tyrosine phosphorylation of 3BP2 is required for optimal FcRγ-mediated phagocytosis and chemokine expression in U937 cells

The adaptor protein c-Abl SH3 domain binding protein-2 (3BP2) is tyrosine phosphorylated by Syk in response to cross-linking of antigen receptors, which in turn activates various immune responses. Recently, a study using the mouse model of cherubism, a dominant inherited disorder caused by mutations...

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Detalles Bibliográficos
Autores principales:	Chihara, Kazuyasu, Kato, Yuji, Yoshiki, Hatsumi, Takeuchi, Kenji, Fujieda, Shigeharu, Sada, Kiyonao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5597638/ https://www.ncbi.nlm.nih.gov/pubmed/28904407 http://dx.doi.org/10.1038/s41598-017-11915-5

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