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Oncogenic human papillomaviruses

Human papillomaviruses (HPVs) are an ancient group of viruses with small, double-stranded DNA circular genomes. They are species-specific and have a strict tropism for mucosal and cutaneous stratified squamous epithelial surfaces of the host. A subset of these viruses has been demonstrated to be the...

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Detalles Bibliográficos
Autor principal: McBride, Alison A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5597740/
https://www.ncbi.nlm.nih.gov/pubmed/28893940
http://dx.doi.org/10.1098/rstb.2016.0273
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author McBride, Alison A.
author_facet McBride, Alison A.
author_sort McBride, Alison A.
collection PubMed
description Human papillomaviruses (HPVs) are an ancient group of viruses with small, double-stranded DNA circular genomes. They are species-specific and have a strict tropism for mucosal and cutaneous stratified squamous epithelial surfaces of the host. A subset of these viruses has been demonstrated to be the causative agent of several human cancers. Here, we review the biology, natural history, evolution and cancer association of the oncogenic HPVs. This article is part of the themed issue ‘Human oncogenic viruses’.
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spelling pubmed-55977402017-09-14 Oncogenic human papillomaviruses McBride, Alison A. Philos Trans R Soc Lond B Biol Sci Articles Human papillomaviruses (HPVs) are an ancient group of viruses with small, double-stranded DNA circular genomes. They are species-specific and have a strict tropism for mucosal and cutaneous stratified squamous epithelial surfaces of the host. A subset of these viruses has been demonstrated to be the causative agent of several human cancers. Here, we review the biology, natural history, evolution and cancer association of the oncogenic HPVs. This article is part of the themed issue ‘Human oncogenic viruses’. The Royal Society 2017-10-19 2017-09-11 /pmc/articles/PMC5597740/ /pubmed/28893940 http://dx.doi.org/10.1098/rstb.2016.0273 Text en © 2017 The Authors. http://creativecommons.org/licenses/by/4.0/ Published by the Royal Society under the terms of the Creative Commons Attribution License http://creativecommons.org/licenses/by/4.0/, which permits unrestricted use, provided the original author and source are credited.
spellingShingle Articles
McBride, Alison A.
Oncogenic human papillomaviruses
title Oncogenic human papillomaviruses
title_full Oncogenic human papillomaviruses
title_fullStr Oncogenic human papillomaviruses
title_full_unstemmed Oncogenic human papillomaviruses
title_short Oncogenic human papillomaviruses
title_sort oncogenic human papillomaviruses
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5597740/
https://www.ncbi.nlm.nih.gov/pubmed/28893940
http://dx.doi.org/10.1098/rstb.2016.0273
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