Complete Genome Sequences of Bordetella pertussis Isolates with Novel Pertactin-Deficient Deletions

Clinical isolates of the respiratory pathogen Bordetella pertussis in the United States have become predominantly deficient for the acellular vaccine immunogen pertactin through various independent mutations. Here, we report the complete genome sequences for four B. pertussis isolates that harbor no...

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Detalles Bibliográficos
Autores principales: Weigand, Michael R., Peng, Yanhui, Cassiday, Pamela K., Loparev, Vladimir N., Johnson, Taccara, Juieng, Phalasy, Nazarian, Elizabeth J., Weening, Keeley, Tondella, M. Lucia, Williams, Margaret M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2017
Materias:
Prokaryotes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5597764/
https://www.ncbi.nlm.nih.gov/pubmed/28912323
http://dx.doi.org/10.1128/genomeA.00973-17
Descripción
Sumario:Clinical isolates of the respiratory pathogen Bordetella pertussis in the United States have become predominantly deficient for the acellular vaccine immunogen pertactin through various independent mutations. Here, we report the complete genome sequences for four B. pertussis isolates that harbor novel deletions responsible for pertactin deficiency.

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