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Exacerbating and reversing lysosomal storage diseases: from yeast to humans

Lysosomal storage diseases (LSDs) arise from monogenic deficiencies in lysosomal proteins and pathways and are characterized by a tissue-wide accumulation of a vast variety of macromolecules, normally specific to each genetic lesion. Strategies for treatment of LSDs commonly depend on reduction of t...

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Detalles Bibliográficos
Autores principales:	Rajakumar, Tamayanthi, Munkacsi, Andrew B., Sturley, Stephen L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Shared Science Publishers OG 2017
Materias:	Microbiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5597791/ https://www.ncbi.nlm.nih.gov/pubmed/28913343 http://dx.doi.org/10.15698/mic2017.09.588

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