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Amifostine does not protect thyroid cancer cells in DNA damaging in vitro models

BACKGROUND: Amifostine is a potent scavenger of reactive oxygen species that is used for the salivary gland protection during therapy with radioactive iodine for thyroid cancer. There are no data on the potential effect of amifostine on thyroid cancer cells. METHODS: We investigated the effects of t...

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Detalles Bibliográficos
Autores principales: Klubo-Gwiezdzinska, Joanna, Costello, John, Jensen, Kirk, Patel, Aneeta, Tkavc, Rok, Van Nostrand, Douglas, Burman, Kenneth D, Wartofsky, Leonard, Vasko, Vasyl
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bioscientifica Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5597971/
https://www.ncbi.nlm.nih.gov/pubmed/28790138
http://dx.doi.org/10.1530/EC-17-0138