Cargando…

Amifostine does not protect thyroid cancer cells in DNA damaging in vitro models

BACKGROUND: Amifostine is a potent scavenger of reactive oxygen species that is used for the salivary gland protection during therapy with radioactive iodine for thyroid cancer. There are no data on the potential effect of amifostine on thyroid cancer cells. METHODS: We investigated the effects of t...

Descripción completa

Detalles Bibliográficos
Autores principales:	Klubo-Gwiezdzinska, Joanna, Costello, John, Jensen, Kirk, Patel, Aneeta, Tkavc, Rok, Van Nostrand, Douglas, Burman, Kenneth D, Wartofsky, Leonard, Vasko, Vasyl
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Bioscientifica Ltd 2017
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5597971/ https://www.ncbi.nlm.nih.gov/pubmed/28790138 http://dx.doi.org/10.1530/EC-17-0138

Ejemplares similares

Cytochrome C Oxidase Subunit 4 (COX4): A Potential Therapeutic Target for the Treatment of Medullary Thyroid Cancer
por: Bikas, Athanasios, et al.
Publicado: (2020)

Levothyroxine Treatment in Pregnancy: Indications, Efficacy, and Therapeutic Regimen
por: Klubo-Gwiezdzinska, Joanna, et al.
Publicado: (2011)

Mitotane induces mitochondrial membrane depolarization and apoptosis in thyroid cancer cells
por: Bikas, Athanasios, et al.
Publicado: (2019)

Detection of BRAFV600E in Liquid Biopsy from Patients with Papillary Thyroid Cancer Is Associated with Tumor Aggressiveness and Response to Therapy
por: Jensen, Kirk, et al.
Publicado: (2020)

Efficacy of Dosimetric Versus Empiric Prescribed Activity of (131)I for Therapy of Differentiated Thyroid Cancer
por: Klubo-Gwiezdzinska, Joanna, et al.
Publicado: (2011)

MON-563 Quantitative Assessment Of BRAF Mutations In Thyroid Cancer Using Droplet Digital PCR.
por: Ylli, Dorina, et al.
Publicado: (2019)

MON-514 Detection of RAS Mutations and RET/PTC Fusions in Thyroid Cancer Using Microfluidic Digital PCR
por: Ylli, Dorina, et al.
Publicado: (2020)

Hashimoto thyroiditis: an evidence-based guide to etiology, diagnosis and treatment
por: Klubo-Gwiezdzinska, Joanna, et al.
Publicado: (2022)

THYROID EMERGENCIES
por: Ylli, Dorina, et al.
Publicado: (2019)

MON-556 Sex-Bias in Clinicopathological Presentation of Patients with Differentiated Thyroid Cancer
por: Shobab, Leila, et al.
Publicado: (2019)

Microfluidic Droplet Digital PCR Is a Powerful Tool for Detection of BRAF and TERT Mutations in Papillary Thyroid Carcinomas
por: Ylli, Dorina, et al.
Publicado: (2019)

OR09-3 Integrins as Potential Molecular Targets in Thyroid Cancer Imaging and Therapy
por: Klubo-Gwiezdzinska, Joanna, et al.
Publicado: (2022)

Limited Utility of Circulating Cell-Free DNA Integrity as a Diagnostic Tool for Differentiating Between Malignant and Benign Thyroid Nodules With Indeterminate Cytology (Bethesda Category III)
por: Thakur, Shilpa, et al.
Publicado: (2019)

SAT519 Association of Free Thyroxine Level With Survival Outcome In Patients With Intermediate And High-Risk Differentiated Thyroid Cancer
por: Ghosh, Raisa, et al.
Publicado: (2023)

Metastatic Differentiated Thyroid Cancer Survival Is Unaffected by Mode of Preparation for (131)I Administration
por: Gomes-Lima, Cristiane J, et al.
Publicado: (2022)

Response to Letter to the Editor from Zandee and Links: “Metastatic Differentiated Thyroid Cancer Survival Is Unaffected by Mode of Preparation for (131)I Administration”
por: Gomes-Lima, Cristiane J, et al.
Publicado: (2023)

Clinical and molecular characterization of thyroid cancer when seen as a second malignant neoplasm
por: Romanelli, Kristen, et al.
Publicado: (2021)

Association of Thyrotropin Suppression With Survival Outcomes in Patients With Intermediate- and High-Risk Differentiated Thyroid Cancer
por: Klubo-Gwiezdzinska, Joanna, et al.
Publicado: (2019)

A Novel Risk Stratification System for Thyroid Nodules With Indeterminate Cytology—A Pilot Cohort Study
por: Gomes-Lima, Cristiane J., et al.
Publicado: (2020)

30 mCi exploratory scan for two-step dosimetric (131)I therapy in differentiated thyroid cancer patients: A novel approach and case report
por: Wu, Di, et al.
Publicado: (2020)

Editorial: Novel Imaging Techniques in the Management of Thyroid Nodules and Autoimmune Thyroid Disease
por: Szczepanek-Parulska, Ewelina, et al.
Publicado: (2019)

Peptide Receptor Radionuclide Therapy in Thyroid Cancer
por: Gubbi, Sriram, et al.
Publicado: (2022)

Response to Letter to the Editor from Sukor et al.: “Evaluation and Treatment of Amiodarone-induced Thyroid Disorders”
por: Ylli, Dorina, et al.
Publicado: (2021)

OR09-5 mTOR Signaling is Associated with Regulation of Mitochondrial Respiration in Thyroid Cancer
por: Klubo-Gwiezdzinska, Joanna, et al.
Publicado: (2022)

The Molecular Landscape of Hürthle Cell Thyroid Cancer Is Associated with Altered Mitochondrial Function—A Comprehensive Review
por: Kumari, Sonam, et al.
Publicado: (2020)

Editorial: Translational research in thyroid cancer, Volume II
por: Cheng, Sheue-yann, et al.
Publicado: (2023)

Editorial: Translational Research in Thyroid Cancer
por: Vasko, Vasyl, et al.
Publicado: (2020)

Novel Targeted Therapies for Metastatic Thyroid Cancer—A Comprehensive Review
por: Al-Jundi, Mohammad, et al.
Publicado: (2020)

Assessment of thyroid function tests and harmonization: opinion on thyroid hormone harmonization
por: Araque, Katherine A., et al.
Publicado: (2019)

Assessment of Thyroid Function in Patients With Alkaptonuria
por: Avadhanula, Shirisha, et al.
Publicado: (2020)

Do Molecular Profiles of Primary Versus Metastatic Radioiodine Refractory Differentiated Thyroid Cancer Differ?
por: Gomes-Lima, Cristiane J., et al.
Publicado: (2021)

SAT556 An Unusual Case of Papillary Thyroid Carcinoma With Biallelic MEN1 Variants In a Patient With MEN1
por: Chuki, Elias, et al.
Publicado: (2023)

OR27-3 A Novel Risk Stratification System for Thyroid Nodules with Indeterminate Cytology: A Pilot Cohort Study
por: Gomes-Lima, Cristiane, et al.
Publicado: (2019)

Breathing the air of mitochondrial respiration via an important oncotarget - mitochondrial glycerophosphate dehydrogenase (mGPDH)
por: Thakur, Shilpa, et al.
Publicado: (2019)

Brain Metastases From Differentiated Thyroid Carcinoma: Prevalence, Current Therapies, and Outcomes
por: Gomes-Lima, Cristiane J, et al.
Publicado: (2018)

Can Reverse T3 Assay Be Employed to Guide T4 vs. T4/T3 Therapy in Hypothyroidism?
por: Gomes-Lima, Cristiane, et al.
Publicado: (2019)

Novel biomarker SYT12 may contribute to predicting papillary thyroid cancer outcomes
por: Jonklaas, J, et al.
Publicado: (2017)

Thyroid Cancer: Focus on Invasion and Metastasis Mechanisms, Therapeutic Target and Drug Treatment
por: Vasko, Vasyl
Publicado: (2023)

The Role of Lithium in Management of Endocrine Tumors—A Comprehensive Review
por: Thakur, Shilpa, et al.
Publicado: (2019)

MON-551 Immediate Cause Of Death In Patients With Thyroid Cancer Progression
por: Ylli, Dorina, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_7g86esg6l2ij9c2i504d5df506