A novel bi-directional promoter system allows tunable recombinant protein production in Pichia pastoris

BACKGROUND: The methylotrophic yeast Pichia pastoris is a well-studied host organism for recombinant protein production, which is usually regulated either by a constitutive promoter (e.g. promoter of glyceraldehyde-3-phosphate dehydrogenase; P(GAP)) or an inducible promoter (e.g. promoter of alcohol...

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Detalles Bibliográficos
Autores principales: Rajamanickam, Vignesh, Metzger, Karl, Schmid, Christian, Spadiut, Oliver
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Technical Notes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5598003/
https://www.ncbi.nlm.nih.gov/pubmed/28903770
http://dx.doi.org/10.1186/s12934-017-0768-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5598003/
https://www.ncbi.nlm.nih.gov/pubmed/28903770
http://dx.doi.org/10.1186/s12934-017-0768-8

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