Modest heterologous protection after Plasmodium falciparum sporozoite immunization: a double-blind randomized controlled clinical trial

BACKGROUND: A highly efficacious vaccine is needed for malaria control and eradication. Immunization with Plasmodium falciparum NF54 parasites under chemoprophylaxis (chemoprophylaxis and sporozoite (CPS)-immunization) induces the most efficient long-lasting protection against a homologous parasite....

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Detalles Bibliográficos
Autores principales: Walk, Jona, Reuling, Isaie J., Behet, Marije C., Meerstein-Kessel, Lisette, Graumans, Wouter, van Gemert, Geert-Jan, Siebelink-Stoter, Rianne, van de Vegte-Bolmer, Marga, Janssen, Thorsten, Teelen, Karina, de Wilt, Johannes H. W., de Mast, Quirijn, van der Ven, André J., Diez Benavente, Ernest, Campino, Susana, Clark, Taane G., Huynen, Martijn A., Hermsen, Cornelus C., Bijker, Else M., Scholzen, Anja, Sauerwein, Robert W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5598044/
https://www.ncbi.nlm.nih.gov/pubmed/28903777
http://dx.doi.org/10.1186/s12916-017-0923-4

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