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Ultrasound-guided direct intrahepatic portosystemic shunt in patients with Budd–Chiari syndrome: Short- and long-term results

BACKGROUND AND AIMS: Budd–Chiari syndrome (BCS) is treated with anticoagulation therapy, transjugular intrahepatic portosystemic shunt (TIPS), angioplasty, and liver transplantation. TIPS is not always technically feasible, due to the complete hepatic venous thrombosis. Direct intrahepatic portosyst...

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Autores principales: Hatzidakis, Adam, Galanakis, Nikolaos, Kehagias, Elias, Samonakis, Dimitrios, Koulentaki, Mairi, Matrella, Erminia, Tsetis, Dimitrios
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Akadémiai Kiadó 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5598128/
https://www.ncbi.nlm.nih.gov/pubmed/28932502
http://dx.doi.org/10.1556/1646.9.2017.2.14
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author Hatzidakis, Adam
Galanakis, Nikolaos
Kehagias, Elias
Samonakis, Dimitrios
Koulentaki, Mairi
Matrella, Erminia
Tsetis, Dimitrios
author_facet Hatzidakis, Adam
Galanakis, Nikolaos
Kehagias, Elias
Samonakis, Dimitrios
Koulentaki, Mairi
Matrella, Erminia
Tsetis, Dimitrios
author_sort Hatzidakis, Adam
collection PubMed
description BACKGROUND AND AIMS: Budd–Chiari syndrome (BCS) is treated with anticoagulation therapy, transjugular intrahepatic portosystemic shunt (TIPS), angioplasty, and liver transplantation. TIPS is not always technically feasible, due to the complete hepatic venous thrombosis. Direct intrahepatic portosystemic shunt (DIPS) is an alternative method for decompression of portal hypertension. This is a retrospective, single-center study aiming to evaluate the outcome of ultrasound (US)-guided DIPS in patients with BCS. MATERIALS AND METHODS: Between 2003 and 2016, six patients with BCS were treated with US-guided DIPS. Polytetrafluoroethylene (PTFE)-covered stents were used in two patients and bare-metal stents in four patients. Mean follow-up time was 71.4 months (range: 21–164). Technical/clinical success, technical difficulties, and complications of DIPS were analyzed. RESULTS: Technical success without complications was achieved in all patients (100%). In one patient, DIPS was performed through the right femoral vein, without significant amelioration of portal hypertension (clinical success 83.3%). In four out of five patients, ascites and variceal bleeding resolved completely and in the other one ascites was relieved. Six- and 12-month primary patency rates were 100% in PTFE-covered stent group when compared with bare-metal stent group, the rates were 33% and 0%, respectively. CONCLUSION: US-guided DIPS is a safe and effective alternative technique for patients with BCS, with significant clinical improvement.
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spelling pubmed-55981282017-09-20 Ultrasound-guided direct intrahepatic portosystemic shunt in patients with Budd–Chiari syndrome: Short- and long-term results Hatzidakis, Adam Galanakis, Nikolaos Kehagias, Elias Samonakis, Dimitrios Koulentaki, Mairi Matrella, Erminia Tsetis, Dimitrios Interv Med Appl Sci Original Paper BACKGROUND AND AIMS: Budd–Chiari syndrome (BCS) is treated with anticoagulation therapy, transjugular intrahepatic portosystemic shunt (TIPS), angioplasty, and liver transplantation. TIPS is not always technically feasible, due to the complete hepatic venous thrombosis. Direct intrahepatic portosystemic shunt (DIPS) is an alternative method for decompression of portal hypertension. This is a retrospective, single-center study aiming to evaluate the outcome of ultrasound (US)-guided DIPS in patients with BCS. MATERIALS AND METHODS: Between 2003 and 2016, six patients with BCS were treated with US-guided DIPS. Polytetrafluoroethylene (PTFE)-covered stents were used in two patients and bare-metal stents in four patients. Mean follow-up time was 71.4 months (range: 21–164). Technical/clinical success, technical difficulties, and complications of DIPS were analyzed. RESULTS: Technical success without complications was achieved in all patients (100%). In one patient, DIPS was performed through the right femoral vein, without significant amelioration of portal hypertension (clinical success 83.3%). In four out of five patients, ascites and variceal bleeding resolved completely and in the other one ascites was relieved. Six- and 12-month primary patency rates were 100% in PTFE-covered stent group when compared with bare-metal stent group, the rates were 33% and 0%, respectively. CONCLUSION: US-guided DIPS is a safe and effective alternative technique for patients with BCS, with significant clinical improvement. Akadémiai Kiadó 2017-06-15 2017-06 /pmc/articles/PMC5598128/ /pubmed/28932502 http://dx.doi.org/10.1556/1646.9.2017.2.14 Text en © 2017 The Author(s) http://creativecommons.org/licenses/by-nc/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium for non-commercial purposes, provided the original author and source are credited.
spellingShingle Original Paper
Hatzidakis, Adam
Galanakis, Nikolaos
Kehagias, Elias
Samonakis, Dimitrios
Koulentaki, Mairi
Matrella, Erminia
Tsetis, Dimitrios
Ultrasound-guided direct intrahepatic portosystemic shunt in patients with Budd–Chiari syndrome: Short- and long-term results
title Ultrasound-guided direct intrahepatic portosystemic shunt in patients with Budd–Chiari syndrome: Short- and long-term results
title_full Ultrasound-guided direct intrahepatic portosystemic shunt in patients with Budd–Chiari syndrome: Short- and long-term results
title_fullStr Ultrasound-guided direct intrahepatic portosystemic shunt in patients with Budd–Chiari syndrome: Short- and long-term results
title_full_unstemmed Ultrasound-guided direct intrahepatic portosystemic shunt in patients with Budd–Chiari syndrome: Short- and long-term results
title_short Ultrasound-guided direct intrahepatic portosystemic shunt in patients with Budd–Chiari syndrome: Short- and long-term results
title_sort ultrasound-guided direct intrahepatic portosystemic shunt in patients with budd–chiari syndrome: short- and long-term results
topic Original Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5598128/
https://www.ncbi.nlm.nih.gov/pubmed/28932502
http://dx.doi.org/10.1556/1646.9.2017.2.14
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