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Prospecting the biodiversity of the fungal family Ustilaginaceae for the production of value-added chemicals

BACKGROUND: Ustilaginaceae (belonging to the smut fungi) are commonly known for their plant pathogenicity. Although these microbes lead to yield reduction of cereal production, they can also have an economically positive side. Ustilaginaceae naturally produce a versatile range of value-added chemica...

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Autores principales: Geiser, Elena, Wiebach, Vincent, Wierckx, Nick, Blank, Lars M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5598272/
https://www.ncbi.nlm.nih.gov/pubmed/28955444
http://dx.doi.org/10.1186/s40694-014-0002-y
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author Geiser, Elena
Wiebach, Vincent
Wierckx, Nick
Blank, Lars M
author_facet Geiser, Elena
Wiebach, Vincent
Wierckx, Nick
Blank, Lars M
author_sort Geiser, Elena
collection PubMed
description BACKGROUND: Ustilaginaceae (belonging to the smut fungi) are commonly known for their plant pathogenicity. Although these microbes lead to yield reduction of cereal production, they can also have an economically positive side. Ustilaginaceae naturally produce a versatile range of value-added chemicals with potential applications in the food, pharmaceutical, and chemical industry. RESULTS: In this study 68 Ustilaginaceae of 13 species were screened for the production of organic acids, polyols, and glycolipids from glucose to characterize their biodiversity and identify potential novel strains for biocatalysis of these valuable chemicals. Ustilago cynodontis, Ustilago maydis, Ustilago avenae, and Sporisorium exsertum were identified as promising production organisms for itaconate, malate, succinate, and erythritol, respectively. The influence of buffer concentration (pH) on acid production was investigated. Selected strains with best itaconate and malate production were characterized in more detail in bioreactor experiments obtaining total acid concentrations of up to 47 ± 1 g L(−1). CONCLUSION: The identification and detailed characterization of these producers of valuable chemicals highlights the potential of these unicellular smut fungi for industrial applications and is a further step towards the biotechnological utilization of Ustilaginaceae. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/s40694-014-0002-y) contains supplementary material, which is available to authorized users.
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spelling pubmed-55982722017-09-27 Prospecting the biodiversity of the fungal family Ustilaginaceae for the production of value-added chemicals Geiser, Elena Wiebach, Vincent Wierckx, Nick Blank, Lars M Fungal Biol Biotechnol Research BACKGROUND: Ustilaginaceae (belonging to the smut fungi) are commonly known for their plant pathogenicity. Although these microbes lead to yield reduction of cereal production, they can also have an economically positive side. Ustilaginaceae naturally produce a versatile range of value-added chemicals with potential applications in the food, pharmaceutical, and chemical industry. RESULTS: In this study 68 Ustilaginaceae of 13 species were screened for the production of organic acids, polyols, and glycolipids from glucose to characterize their biodiversity and identify potential novel strains for biocatalysis of these valuable chemicals. Ustilago cynodontis, Ustilago maydis, Ustilago avenae, and Sporisorium exsertum were identified as promising production organisms for itaconate, malate, succinate, and erythritol, respectively. The influence of buffer concentration (pH) on acid production was investigated. Selected strains with best itaconate and malate production were characterized in more detail in bioreactor experiments obtaining total acid concentrations of up to 47 ± 1 g L(−1). CONCLUSION: The identification and detailed characterization of these producers of valuable chemicals highlights the potential of these unicellular smut fungi for industrial applications and is a further step towards the biotechnological utilization of Ustilaginaceae. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/s40694-014-0002-y) contains supplementary material, which is available to authorized users. BioMed Central 2014-11-01 /pmc/articles/PMC5598272/ /pubmed/28955444 http://dx.doi.org/10.1186/s40694-014-0002-y Text en © Geiser et al.; licensee BioMed Central Ltd. 2014 This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Research
Geiser, Elena
Wiebach, Vincent
Wierckx, Nick
Blank, Lars M
Prospecting the biodiversity of the fungal family Ustilaginaceae for the production of value-added chemicals
title Prospecting the biodiversity of the fungal family Ustilaginaceae for the production of value-added chemicals
title_full Prospecting the biodiversity of the fungal family Ustilaginaceae for the production of value-added chemicals
title_fullStr Prospecting the biodiversity of the fungal family Ustilaginaceae for the production of value-added chemicals
title_full_unstemmed Prospecting the biodiversity of the fungal family Ustilaginaceae for the production of value-added chemicals
title_short Prospecting the biodiversity of the fungal family Ustilaginaceae for the production of value-added chemicals
title_sort prospecting the biodiversity of the fungal family ustilaginaceae for the production of value-added chemicals
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5598272/
https://www.ncbi.nlm.nih.gov/pubmed/28955444
http://dx.doi.org/10.1186/s40694-014-0002-y
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