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Clozapine-induced cardiotoxicity in rats: Involvement of tumour necrosis factor alpha, NF-κβ and caspase-3

Clozapine, an ideal antipsychotic drug for the treatment of resistant schizophrenia, is considered the most underutilised treatment for schizophrenia. However, safety concerns have been raised about clozapine-induced cardiotoxicity, which may lead to sudden death, particularly in young patients. The...

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Detalles Bibliográficos
Autores principales: Abdel-Wahab, Basel A., Metwally, Metwally E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5598316/
https://www.ncbi.nlm.nih.gov/pubmed/28962331
http://dx.doi.org/10.1016/j.toxrep.2014.11.012