Reduced kidney levels of lysophosphatidic acids in rats after chronic administration of aristolochic acid: Its possible protective role in renal fibrosis

Aristolochic acid (AA) is considered to be a causative agent for progressive interstitial renal fibrosis, leading to AA nephropathy. Lysophosphatidic acid (LPA) is a mediator in the onset of renal fibrosis. In this study, we analyzed the molecular species of LPA and its precursor lysophospholipids i...

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Detalles Bibliográficos
Autores principales: Tsutsumi, Toshihiko, Yamakawa, Syougo, Ishihara, Akira, Yamamoto, Aimi, Tanaka, Tamotsu, Tokumura, Akira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5598376/
https://www.ncbi.nlm.nih.gov/pubmed/28962344
http://dx.doi.org/10.1016/j.toxrep.2015.02.012

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