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Effect of iron overload on furin expression in wild-type and β-thalassemic mice

Furin is a proprotein convertase enzyme. In the liver, it cleaves prohepcidin to form active hepcidin-25, which regulates systemic iron homeostasis. Hepcidin deficiency is a component of several iron overload disorders, including β-thalassemia. Several studies have identified factors that repress he...

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Detalles Bibliográficos
Autores principales: Wichaiyo, Surasak, Yatmark, Paranee, Morales Vargas, Ronald Enrique, Sanvarinda, Pimtip, Svasti, Saovaros, Fucharoen, Suthat, Morales, Noppawan Phumala
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5598392/
https://www.ncbi.nlm.nih.gov/pubmed/28962376
http://dx.doi.org/10.1016/j.toxrep.2015.01.004

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