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Chitosan nanoparticles and quercetin modulate gene expression and prevent the genotoxicity of aflatoxin B(1) in rat liver

The aims of the current study were to prepare chitosan nanoparticles (CNPs) and to evaluate its protective role alone or in combination with quercetin (Q) against AFB(1)-induce cytotoxicity in rats. Male Sprague-Dawley rats were divided into 12 groups and treated orally for 4 weeks as follow: the co...

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Detalles Bibliográficos
Autores principales: Abdel-Wahhab, Mosaad A., Aljawish, Abdulhadi, El-Nekeety, Aziza A., Abdel-Aiezm, Sekena H., Abdel-Kader, Heba A.M., Rihn, Bertrand H., Joubert, Olivier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5598511/
https://www.ncbi.nlm.nih.gov/pubmed/28962409
http://dx.doi.org/10.1016/j.toxrep.2015.05.007