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Cationic lipid-based nanoparticles mediate functional delivery of acetate to tumor cells in vivo leading to significant anticancer effects
Metabolic reengineering using nanoparticle delivery represents an innovative therapeutic approach to normalizing the deregulation of cellular metabolism underlying many diseases, including cancer. Here, we demonstrated a unique and novel application to the treatment of malignancy using a short-chain...
Autores principales: | Brody, Leigh P, Sahuri-Arisoylu, Meliz, Parkinson, James R, Parkes, Harry G, So, Po Wah, Hajji, Nabil, Thomas, E Louise, Frost, Gary S, Miller, Andrew D, Bell, Jimmy D |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5598551/ https://www.ncbi.nlm.nih.gov/pubmed/28932113 http://dx.doi.org/10.2147/IJN.S135968 |
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