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Investigating DNA supercoiling in eukaryotic genomes
Supercoiling is a fundamental property of DNA, generated by polymerases and other DNA-binding proteins as a consequence of separating/bending the DNA double helix. DNA supercoiling plays a key role in gene expression and genome organization, but has proved difficult to study in eukaryotes because of...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5598747/ https://www.ncbi.nlm.nih.gov/pubmed/28444308 http://dx.doi.org/10.1093/bfgp/elx007 |