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More Dose-dependent Side Effects with Mercaptopurine over Azathioprine in IBD Treatment Due to Relatively Higher Dosing
BACKGROUND: There are substantial global differences in the preference for mercaptopurine (MP) or its prodrug azathioprine (AZA) as first-choice thiopurine to treat inflammatory bowel diseases. Studies comparing both agents are scarce. Our aim was to compare AZA and MP in thiopurine-naive patients w...
Autores principales: | Broekman, Mark M. T. J., Coenen, Marieke J. H., van Marrewijk, Corine J., Wanten, Geert J. A., Wong, Dennis R., Verbeek, Andre L. M., Klungel, Olaf H., Hooymans, Piet M., Guchelaar, Henk-Jan, Scheffer, Hans, Derijks, Luc J. J., de Jong, Dirk J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Lippincott Williams & Wilkins
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5598908/ https://www.ncbi.nlm.nih.gov/pubmed/28644183 http://dx.doi.org/10.1097/MIB.0000000000001163 |
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