Longitudinal multiparameter single-cell analysis of macaques immunized with pneumococcal protein-conjugated or unconjugated polysaccharide vaccines reveals distinct antigen specific memory B cell repertoires

BACKGROUND: The efficacy of protein-conjugated pneumococcal polysaccharide vaccines has been well characterized for children. The level of protection conferred by unconjugated polysaccharide vaccines remains less clear, particularly for elderly individuals who have had prior antigenic experience thr...

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Detalles Bibliográficos
Autores principales: Jia, Bin, McNeil, Lisa K., Dupont, Christopher D., Tsioris, Konstantinos, Barry, Rachel M., Scully, Ingrid L., Ogunniyi, Adebola O., Gonzalez, Christopher, Pride, Michael W., Gierahn, Todd M., Liberator, Paul A., Jansen, Kathrin U., Love, J. Christopher
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5598952/
https://www.ncbi.nlm.nih.gov/pubmed/28910279
http://dx.doi.org/10.1371/journal.pone.0183738

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