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Acute exacerbations of COPD: risk factors for failure and relapse

Acute exacerbations are a leading cause of worsening COPD in terms of lung function decline, quality of life, and survival. They also have a relevant economic burden on the health care system. Determining the risk factors for acute exacerbation and early relapse could be a crucial element for a bett...

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Detalles Bibliográficos
Autores principales: Mantero, Marco, Rogliani, Paola, Di Pasquale, Marta, Polverino, Eva, Crisafulli, Ernesto, Guerrero, Monica, Gramegna, Andrea, Cazzola, Mario, Blasi, Francesco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5598966/
https://www.ncbi.nlm.nih.gov/pubmed/28932112
http://dx.doi.org/10.2147/COPD.S145253
Descripción
Sumario:Acute exacerbations are a leading cause of worsening COPD in terms of lung function decline, quality of life, and survival. They also have a relevant economic burden on the health care system. Determining the risk factors for acute exacerbation and early relapse could be a crucial element for a better management of COPD patients. This review analyzes the current knowledge and underlines the main risk factors for recurrent acute exacerbations. Comprehensive evaluation of COPD patients during stable phase and exacerbation could contribute to prevent treatment failure and relapses.