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Differential impact of the dual CCR2/CCR5 inhibitor cenicriviroc on migration of monocyte and lymphocyte subsets in acute liver injury

A hallmark of acute hepatic injury is the recruitment of neutrophils, monocytes and lymphocytes, including natural killer (NK) or T cells, towards areas of inflammation. The recruitment of leukocytes from their reservoirs bone marrow or spleen into the liver is directed by chemokines such as CCL2 (f...

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Detalles Bibliográficos
Autores principales: Puengel, Tobias, Krenkel, Oliver, Kohlhepp, Marlene, Lefebvre, Eric, Luedde, Tom, Trautwein, Christian, Tacke, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5598992/
https://www.ncbi.nlm.nih.gov/pubmed/28910354
http://dx.doi.org/10.1371/journal.pone.0184694