Inhibition of EZH2 Promotes Human Embryonic Stem Cell Differentiation into Mesoderm by Reducing H3K27me3

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Mesoderm derived from human embryonic stem cells (hESCs) is a major source of the mesenchymal stem/stromal cells (MSCs) that can differentiate into osteoblasts and chondrocytes for tissue regeneration. While significant progress has been made in understanding of molecular mechanisms of hESC differen...

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Detalles Bibliográficos
Autores principales: Yu, Yongxin, Deng, Peng, Yu, Bo, Szymanski, John M., Aghaloo, Tara, Hong, Christine, Wang, Cun-Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5599223/
https://www.ncbi.nlm.nih.gov/pubmed/28826853
http://dx.doi.org/10.1016/j.stemcr.2017.07.016
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