Cargando…

Mitigating Ischemic Injury of Stem Cell-Derived Insulin-Producing Cells after Transplant

The advent of large-scale in vitro differentiation of human stem cell-derived insulin-producing cells (SCIPC) has brought us closer to treating diabetes using stem cell technology. However, decades of experiences from islet transplantation show that ischemia-induced islet cell death after transplant...

Descripción completa

Detalles Bibliográficos
Autores principales:	Faleo, Gaetano, Russ, Holger A., Wisel, Steven, Parent, Audrey V., Nguyen, Vinh, Nair, Gopika G., Freise, Jonathan E., Villanueva, Karina E., Szot, Gregory L., Hebrok, Matthias, Tang, Qizhi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5599226/ https://www.ncbi.nlm.nih.gov/pubmed/28803916 http://dx.doi.org/10.1016/j.stemcr.2017.07.012

Ejemplares similares

Replenishable prevascularized cell encapsulation devices increase graft survival and function in the subcutaneous space
por: Chendke, Gauree S., et al.
Publicado: (2023)

Development of a scalable method to isolate subsets of stem cell-derived pancreatic islet cells
por: Parent, Audrey V., et al.
Publicado: (2022)

LIN28B Impairs the Transition of hESC-Derived β Cells from the Juvenile to Adult State
por: Zhou, Xin, et al.
Publicado: (2019)

Rapid Modification of Workflows and Fellow Staffing at a Single Transplant Center to Address the COVID-19 Crisis
por: Thiessen, Carrie, et al.
Publicado: (2020)

Silicon nanopore membrane (SNM) for islet encapsulation and immunoisolation under convective transport
por: Song, Shang, et al.
Publicado: (2016)

Stem cell-based multi-tissue platforms to model human autoimmune diabetes
por: Leavens, Karla F., et al.
Publicado: (2022)

Factors Expressed by Murine Embryonic Pancreatic Mesenchyme Enhance Generation of Insulin-Producing Cells From hESCs
por: Guo, Tingxia, et al.
Publicado: (2013)

Human pancreatic beta-like cells converted from fibroblasts
por: Zhu, Saiyong, et al.
Publicado: (2016)

Precision Engineering of an Anti-HLA-A2 Chimeric Antigen Receptor in Regulatory T Cells for Transplant Immune Tolerance
por: Muller, Yannick D., et al.
Publicado: (2021)

Dynamic Proteomic Analysis of Pancreatic Mesenchyme Reveals Novel Factors That Enhance Human Embryonic Stem Cell to Pancreatic Cell Differentiation
por: Russ, Holger A., et al.
Publicado: (2016)

Replication confers β cell immaturity
por: Puri, Sapna, et al.
Publicado: (2018)

A Multi-Modal Approach to Islet and Pancreas Transplantation With Calcineurin-Sparing Immunosuppression Maintains Long-Term Insulin Independence in Patients With Type I Diabetes
por: Wisel, Steven A., et al.
Publicado: (2023)

Loss of the transcription factor MAFB limits β-cell derivation from human PSCs
por: Russell, Ronan, et al.
Publicado: (2020)

All mixed up: defining roles for β-cell subtypes in mature islets
por: Liu, Jennifer S.E., et al.
Publicado: (2017)

Human islets contain four distinct subtypes of β cells
por: Dorrell, Craig, et al.
Publicado: (2016)

Mitigating sarcoplasmic reticulum stress limits disuse-induced muscle loss in hindlimb unloaded mice
por: Khan, Amir Ali, et al.
Publicado: (2022)

Stem Cell-Based Clinical Trials for Diabetes Mellitus
por: de Klerk, Eleonora, et al.
Publicado: (2021)

Expansion and conversion of human pancreatic ductal cells into insulin-secreting endocrine cells
por: Lee, Jonghyeob, et al.
Publicado: (2013)

Hedgehog Signaling in Pancreas Epithelium Regulates Embryonic Organ Formation and Adult β-Cell Function
por: Lau, Janet, et al.
Publicado: (2010)

Multiplexed microfluidic platform for stem-cell derived pancreatic islet β cells
por: Goswami, Ishan, et al.
Publicado: (2022)

Transcriptional changes and the role of ONECUT1 in hPSC pancreatic differentiation
por: Heller, Sandra, et al.
Publicado: (2021)

In Vitro–expanded Antigen-specific Regulatory T Cells Suppress Autoimmune Diabetes
por: Tang, Qizhi, et al.
Publicado: (2004)

PTF1a Activity in Enriched Posterior Foregut Endoderm, but Not Definitive Endoderm, Leads to Enhanced Pancreatic Differentiation in an In Vitro Mouse ESC-Based Model
por: Nair, Gopika G., et al.
Publicado: (2016)

Brg1 promotes both tumor-suppressive and oncogenic activities at distinct stages of pancreatic cancer formation
por: Roy, Nilotpal, et al.
Publicado: (2015)

Evolution of Insulin Delivery Devices: From Syringes, Pens, and Pumps to DIY Artificial Pancreas
por: Kesavadev, Jothydev, et al.
Publicado: (2020)

VHL-mediated disruption of Sox9 activity compromises β-cell identity and results in diabetes mellitus
por: Puri, Sapna, et al.
Publicado: (2013)

A Role for von Hippel-Lindau Protein in Pancreatic β-Cell Function
por: Puri, Sapna, et al.
Publicado: (2009)

Ability of Local Clearance of Senescent Cells in Ipsilateral Hemisphere to Mitigate Acute Ischemic Brain Injury in Mice
por: Lu, Kuan-Jung, et al.
Publicado: (2023)

Metoprolol Mitigates Ischemic Heart Remodeling and Fibrosis by Increasing the Expression of AKAP5 in Ischemic Heart
por: Zhu, Feng, et al.
Publicado: (2022)

Insulin-Producing Cells Generated from Dedifferentiated Human Pancreatic Beta Cells Expanded In Vitro
por: Russ, Holger A., et al.
Publicado: (2011)

Simultaneous thoracic and abdominal donation after circulatory death organ recovery: the abdominal surgeon's perspective
por: Thiessen, Carrie, et al.
Publicado: (2023)

Retracted: Metoprolol Mitigates Ischemic Heart Remodeling and Fibrosis by Increasing the Expression of AKAP5 in Ischemic Heart
por: Longevity, Oxidative Medicine and Cellular
Publicado: (2023)

Intranasal insulin neuroprotection in ischemic stroke
por: Lioutas, Vasileios-Arsenios, et al.
Publicado: (2016)

Spontaneous Tumour Lysis Syndrome in Mantle Cell Lymphoma: A Case Study
por: Taha, Nadia, et al.
Publicado: (2022)

Assessing the role of plasma-engineered acceptor-like intra- and inter-grain boundaries of heterogeneous WS(2)–WO(3) nanosheets for photocurrent characteristics
por: Gopakumar, Gopika, et al.
Publicado: (2020)

Guanxintai Exerts Protective Effects on Ischemic Cardiomyocytes by Mitigating Oxidative Stress
por: Yang, Jing, et al.
Publicado: (2017)

MORIN MITIGATES OXIDATIVE STRESS, APOPTOSIS AND INFLAMMATION IN CEREBRAL ISCHEMIC RATS
por: Chen, Yanrong, et al.
Publicado: (2017)

hUCMSCs Mitigate LPS-Induced Trained Immunity in Ischemic Stroke
por: Feng, Yi-wei, et al.
Publicado: (2020)

Ischemic Postconditioning Mitigates Retinopathy in Tree Shrews with Diabetic Cerebral Ischemia
por: Zhao, Ling, et al.
Publicado: (2020)

Dicer Regulates Differentiation and Viability during Mouse Pancreatic Cancer Initiation
por: Morris, John P., et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_e3le2poat2vk48na0s343rg6nu