Tissue-specific regulation of BMP signaling by Drosophila N-glycanase 1

Mutations in the human N-glycanase 1 (NGLY1) cause a rare, multisystem congenital disorder with global developmental delay. However, the mechanisms by which NGLY1 and its homologs regulate embryonic development are not known. Here we show that Drosophila Pngl encodes an N-glycanase and exhibits a hi...

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Detalles Bibliográficos
Autores principales: Galeone, Antonio, Han, Seung Yeop, Huang, Chengcheng, Hosomi, Akira, Suzuki, Tadashi, Jafar-Nejad, Hamed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Developmental Biology and Stem Cells
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5599231/
https://www.ncbi.nlm.nih.gov/pubmed/28826503
http://dx.doi.org/10.7554/eLife.27612

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5599231/
https://www.ncbi.nlm.nih.gov/pubmed/28826503
http://dx.doi.org/10.7554/eLife.27612

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