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Neural Crest Cell Implantation Restores Enteric Nervous System Function and Alters the Gastrointestinal Transcriptome in Human Tissue-Engineered Small Intestine
Acquired or congenital disruption in enteric nervous system (ENS) development or function can lead to significant mechanical dysmotility. ENS restoration through cellular transplantation may provide a cure for enteric neuropathies. We have previously generated human pluripotent stem cell (hPSC)-deri...
Autores principales: | Schlieve, Christopher R., Fowler, Kathryn L., Thornton, Matthew, Huang, Sha, Hajjali, Ibrahim, Hou, Xiaogang, Grubbs, Brendan, Spence, Jason R., Grikscheit, Tracy C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5599241/ https://www.ncbi.nlm.nih.gov/pubmed/28803915 http://dx.doi.org/10.1016/j.stemcr.2017.07.017 |
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