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Recapitulation of Human Retinal Development from Human Pluripotent Stem Cells Generates Transplantable Populations of Cone Photoreceptors
Transplantation of rod photoreceptors, derived either from neonatal retinae or pluripotent stem cells (PSCs), can restore rod-mediated visual function in murine models of inherited blindness. However, humans depend more upon cone photoreceptors that are required for daylight, color, and high-acuity...
Autores principales: | Gonzalez-Cordero, Anai, Kruczek, Kamil, Naeem, Arifa, Fernando, Milan, Kloc, Magdalena, Ribeiro, Joana, Goh, Debbie, Duran, Yanai, Blackford, Samuel J.I., Abelleira-Hervas, Laura, Sampson, Robert D., Shum, Ian O., Branch, Matthew J., Gardner, Peter J., Sowden, Jane C., Bainbridge, James W.B., Smith, Alexander J., West, Emma L., Pearson, Rachael A., Ali, Robin R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5599247/ https://www.ncbi.nlm.nih.gov/pubmed/28844659 http://dx.doi.org/10.1016/j.stemcr.2017.07.022 |
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