Germline Stem Cell Activity Is Sustained by SALL4-Dependent Silencing of Distinct Tumor Suppressor Genes

Sustained spermatogenesis in adult males and fertility recovery following germ cell depletion are dependent on undifferentiated spermatogonia. We previously demonstrated a key role for the transcription factor SALL4 in spermatogonial differentiation. However, whether SALL4 has broader roles within s...

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Detalles Bibliográficos
Autores principales: Chan, Ai-Leen, La, Hue M., Legrand, Julien M.D., Mäkelä, Juho-Antti, Eichenlaub, Michael, De Seram, Mia, Ramialison, Mirana, Hobbs, Robin M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5599261/
https://www.ncbi.nlm.nih.gov/pubmed/28867346
http://dx.doi.org/10.1016/j.stemcr.2017.08.001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5599261/
https://www.ncbi.nlm.nih.gov/pubmed/28867346
http://dx.doi.org/10.1016/j.stemcr.2017.08.001

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