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Germline Stem Cell Activity Is Sustained by SALL4-Dependent Silencing of Distinct Tumor Suppressor Genes
Sustained spermatogenesis in adult males and fertility recovery following germ cell depletion are dependent on undifferentiated spermatogonia. We previously demonstrated a key role for the transcription factor SALL4 in spermatogonial differentiation. However, whether SALL4 has broader roles within s...
Autores principales: | Chan, Ai-Leen, La, Hue M., Legrand, Julien M.D., Mäkelä, Juho-Antti, Eichenlaub, Michael, De Seram, Mia, Ramialison, Mirana, Hobbs, Robin M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5599261/ https://www.ncbi.nlm.nih.gov/pubmed/28867346 http://dx.doi.org/10.1016/j.stemcr.2017.08.001 |
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