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Mutagenesis of the NaChBac sodium channel discloses a functional role for a conserved S6 asparagine
Asparagine is conserved in the S6 transmembrane segments of all voltage-gated sodium, calcium, and TRP channels identified to date. A broad spectrum of channelopathies including cardiac arrhythmias, epilepsy, muscle diseases, and pain disorders is associated with its mutation. To investigate its eff...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer International Publishing
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5599482/ https://www.ncbi.nlm.nih.gov/pubmed/28825121 http://dx.doi.org/10.1007/s00249-017-1246-2 |