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Using a Novel Microfabricated Model of the Alveolar-Capillary Barrier to Investigate the Effect of Matrix Structure on Atelectrauma

The alveolar-capillary barrier is composed of epithelial and endothelial cells interacting across a fibrous extracelluar matrix (ECM). Although remodeling of the ECM occurs during several lung disorders, it is not known how fiber structure and mechanics influences cell injury during cyclic airway re...

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Detalles Bibliográficos
Autores principales: Higuita-Castro, N., Nelson, M. T., Shukla, V., Agudelo-Garcia, P. A., Zhang, W., Duarte-Sanmiguel, S. M., Englert, J. A., Lannutti, J. J., Hansford, D. J., Ghadiali, S. N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5599538/
https://www.ncbi.nlm.nih.gov/pubmed/28912466
http://dx.doi.org/10.1038/s41598-017-12044-9