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Using a Novel Microfabricated Model of the Alveolar-Capillary Barrier to Investigate the Effect of Matrix Structure on Atelectrauma
The alveolar-capillary barrier is composed of epithelial and endothelial cells interacting across a fibrous extracelluar matrix (ECM). Although remodeling of the ECM occurs during several lung disorders, it is not known how fiber structure and mechanics influences cell injury during cyclic airway re...
Autores principales: | Higuita-Castro, N., Nelson, M. T., Shukla, V., Agudelo-Garcia, P. A., Zhang, W., Duarte-Sanmiguel, S. M., Englert, J. A., Lannutti, J. J., Hansford, D. J., Ghadiali, S. N. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5599538/ https://www.ncbi.nlm.nih.gov/pubmed/28912466 http://dx.doi.org/10.1038/s41598-017-12044-9 |
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