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Iron deposition is associated with differential macrophage infiltration and therapeutic response to iron chelation in prostate cancer

Immune cells such as macrophages are drivers and biomarkers of most cancers. Scoring macrophage infiltration in tumor tissue provides a prognostic assessment that is correlated with disease outcome and therapeutic response, but generally requires invasive biopsy. Routine detection of hemosiderin iro...

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Detalles Bibliográficos
Autores principales: Leftin, Avigdor, Zhao, Huiyong, Turkekul, Mesru, de Stanchina, Elisa, Manova, Katia, Koutcher, Jason A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5599545/
https://www.ncbi.nlm.nih.gov/pubmed/28912459
http://dx.doi.org/10.1038/s41598-017-11899-2