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Iron deposition is associated with differential macrophage infiltration and therapeutic response to iron chelation in prostate cancer
Immune cells such as macrophages are drivers and biomarkers of most cancers. Scoring macrophage infiltration in tumor tissue provides a prognostic assessment that is correlated with disease outcome and therapeutic response, but generally requires invasive biopsy. Routine detection of hemosiderin iro...
Autores principales: | Leftin, Avigdor, Zhao, Huiyong, Turkekul, Mesru, de Stanchina, Elisa, Manova, Katia, Koutcher, Jason A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5599545/ https://www.ncbi.nlm.nih.gov/pubmed/28912459 http://dx.doi.org/10.1038/s41598-017-11899-2 |
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