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Niche harmony search algorithm for detecting complex disease associated high-order SNP combinations
Genome-wide association study is especially challenging in detecting high-order disease-causing models due to model diversity, possible low or even no marginal effect of the model, and extraordinary search and computations. In this paper, we propose a niche harmony search algorithm where joint entro...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5599559/ https://www.ncbi.nlm.nih.gov/pubmed/28912584 http://dx.doi.org/10.1038/s41598-017-11064-9 |