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Global organization of a binding site network gives insight into evolution and structure-function relationships of proteins

The global organization of protein binding sites is analyzed by constructing a weighted network of binding sites based on their structural similarities and detecting communities of structurally similar binding sites based on the minimum description length principle. The analysis reveals that there a...

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Detalles Bibliográficos
Autores principales: Lee, Juyong, Konc, Janez, Janežič, Dušanka, Brooks, Bernard R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5599562/
https://www.ncbi.nlm.nih.gov/pubmed/28912495
http://dx.doi.org/10.1038/s41598-017-10412-z

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