Of Mice and Men: Empirical Support for the Population-Based Social Epistasis Amplification Model (a Comment on Kalbassi et al., 2017)

This commentary article offers new perspective on recent research investigating the behavioral and social ecological effects of a mutation related to autism spectrum disorders in mice. The authors explain the consistency of this research on mice with predictions advanced by a theory of the role of m...

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Detalles Bibliográficos
Autores principales: Sarraf, Matthew Alexandar, Woodley of Menie, Michael Anthony
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2017
Materias:
Commentary
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5599588/
https://www.ncbi.nlm.nih.gov/pubmed/28920075
http://dx.doi.org/10.1523/ENEURO.0280-17.2017
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author Sarraf, Matthew Alexandar
Woodley of Menie, Michael Anthony
author_facet Sarraf, Matthew Alexandar
Woodley of Menie, Michael Anthony
author_sort Sarraf, Matthew Alexandar
collection PubMed
description This commentary article offers new perspective on recent research investigating the behavioral and social ecological effects of a mutation related to autism spectrum disorders in mice. The authors explain the consistency of this research on mice with predictions advanced by a theory of the role of mutations in altering interorganismal gene-gene interactions (social epistasis) in social species including humans, known as the social epistasis amplification model. The potential significance of the mouse research for understanding contemporary human behavioral trends is explored.
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spelling pubmed-55995882017-09-29 Of Mice and Men: Empirical Support for the Population-Based Social Epistasis Amplification Model (a Comment on Kalbassi et al., 2017) Sarraf, Matthew Alexandar Woodley of Menie, Michael Anthony eNeuro Commentary This commentary article offers new perspective on recent research investigating the behavioral and social ecological effects of a mutation related to autism spectrum disorders in mice. The authors explain the consistency of this research on mice with predictions advanced by a theory of the role of mutations in altering interorganismal gene-gene interactions (social epistasis) in social species including humans, known as the social epistasis amplification model. The potential significance of the mouse research for understanding contemporary human behavioral trends is explored. Society for Neuroscience 2017-09-21 /pmc/articles/PMC5599588/ /pubmed/28920075 http://dx.doi.org/10.1523/ENEURO.0280-17.2017 Text en Copyright © 2017 Sarraf and Woodley of Menie http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.
spellingShingle Commentary
Sarraf, Matthew Alexandar
Woodley of Menie, Michael Anthony
Of Mice and Men: Empirical Support for the Population-Based Social Epistasis Amplification Model (a Comment on Kalbassi et al., 2017)
title Of Mice and Men: Empirical Support for the Population-Based Social Epistasis Amplification Model (a Comment on Kalbassi et al., 2017)
title_full Of Mice and Men: Empirical Support for the Population-Based Social Epistasis Amplification Model (a Comment on Kalbassi et al., 2017)
title_fullStr Of Mice and Men: Empirical Support for the Population-Based Social Epistasis Amplification Model (a Comment on Kalbassi et al., 2017)
title_full_unstemmed Of Mice and Men: Empirical Support for the Population-Based Social Epistasis Amplification Model (a Comment on Kalbassi et al., 2017)
title_short Of Mice and Men: Empirical Support for the Population-Based Social Epistasis Amplification Model (a Comment on Kalbassi et al., 2017)
title_sort of mice and men: empirical support for the population-based social epistasis amplification model (a comment on kalbassi et al., 2017)
topic Commentary
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5599588/
https://www.ncbi.nlm.nih.gov/pubmed/28920075
http://dx.doi.org/10.1523/ENEURO.0280-17.2017
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