Cargando…

An injectable hydrogel enhances tissue repair after spinal cord injury by promoting extracellular matrix remodeling

The cystic cavity that develops following injuries to brain or spinal cord is a major obstacle for tissue repair in central nervous system (CNS). Here we report that injection of imidazole-poly(organophosphazenes) (I-5), a hydrogel with thermosensitive sol–gel transition behavior, almost completely...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hong, Le Thi Anh, Kim, Young-Min, Park, Hee Hwan, Hwang, Dong Hoon, Cui, Yuexian, Lee, Eun Mi, Yahn, Stephanie, Lee, Jae K., Song, Soo-Chang, Kim, Byung Gon
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5599609/ https://www.ncbi.nlm.nih.gov/pubmed/28912446 http://dx.doi.org/10.1038/s41467-017-00583-8

Ejemplares similares

Insulin-like Growth Factor-1 Receptor Dictates Beneficial Effects of Treadmill Training by Regulating Survival and Migration of Neural Stem Cell Grafts in the Injured Spinal Cord
por: Hwang, Dong Hoon, et al.
Publicado: (2018)

An injectable, self-healing, electroconductive extracellular matrix-based hydrogel for enhancing tissue repair after traumatic spinal cord injury
por: Luo, Yian, et al.
Publicado: (2021)

Injectable hydrogels in central nervous system: Unique and novel platforms for promoting extracellular matrix remodeling and tissue engineering
por: Hasanzadeh, Elham, et al.
Publicado: (2023)

Organotypic Spinal Cord Slice Culture to Study Neural Stem/Progenitor Cell Microenvironment in the Injured Spinal Cord
por: Kim, Hyuk Min, et al.
Publicado: (2010)

Application of Injectable Hydrogels as Delivery Systems in Spinal Cord Injury
por: Ji, Rong, et al.
Publicado: (2023)

Molecular and Cellular Changes in the Lumbar Spinal Cord following Thoracic Injury: Regulation by Treadmill Locomotor Training
por: Shin, Hae Young, et al.
Publicado: (2014)

Fortuitous benefits of activity-based rehabilitation in stem cell-based therapy for spinal cord repair: enhancing graft survival
por: Hwang, Dong Hoon, et al.
Publicado: (2015)

An Injectable, Calcium Responsive Composite Hydrogel for the Treatment of Acute Spinal Cord Injury
por: McKay, Christopher A., et al.
Publicado: (2014)

Tissue extracellular matrix hydrogels as alternatives to Matrigel for culturing gastrointestinal organoids
por: Kim, Suran, et al.
Publicado: (2022)

Extracellular matrix-templating fibrous hydrogels promote ovarian tissue remodeling and oocyte growth
por: Nason-Tomaszewski, Claire E., et al.
Publicado: (2023)

Hydrogels as Extracellular Matrix Analogs
por: González-Díaz, Eva C., et al.
Publicado: (2016)

Extracellular matrix remodelling in COPD
por: Karakioulaki, Meropi, et al.
Publicado: (2020)

Zwitterionic Hydrogel Activates Autophagy to Promote Extracellular Matrix Remodeling for Improved Pressure Ulcer Healing
por: Li, Yuan, et al.
Publicado: (2021)

Photoreactive-proton-generating hyaluronidase/albumin nanoparticles-loaded PEG-hydrogel enhances antitumor efficacy and disruption of the hyaluronic acid extracellular matrix in AsPC-1 tumors
por: Lee, Woo Tak, et al.
Publicado: (2021)

Ulipristal acetate induces cell cycle delay and remodeling of extracellular matrix
por: Shin, So-Jin, et al.
Publicado: (2018)

Single-cell analysis of the cellular heterogeneity and interactions in the injured mouse spinal cord
por: Milich, Lindsay M., et al.
Publicado: (2021)

Effect of Decellularized Extracellular Matrix Bioscaffolds Derived from Fibroblasts on Skin Wound Healing and Remodeling
por: Kim, Hyo-Sung, et al.
Publicado: (2022)

An injectable and self-healing hydrogel with controlled release of curcumin to repair spinal cord injury
por: Luo, Jinghua, et al.
Publicado: (2021)

Extracellular Matrix Hydrogel Promotes Tissue Remodeling, Arteriogenesis, and Perfusion in a Rat Hindlimb Ischemia Model
por: Ungerleider, Jessica L., et al.
Publicado: (2016)

Operation spinal cord regeneration: Patterning information residing in extracellular matrix glycosaminoglycans
por: Lu, Alexander, et al.
Publicado: (2020)

Extracellular Matrix Remodeling in Human Disease
por: Sonbol, Hala Salim
Publicado: (2018)

Extracellular Matrix Remodeling of the Umbilical Cord in Pre-eclampsia as a Risk Factor for Fetal Hypertension
por: Romanowicz, Lech, et al.
Publicado: (2011)

Extracellular Vesicles and Matrix Remodeling Enzymes: The Emerging Roles in Extracellular Matrix Remodeling, Progression of Diseases and Tissue Repair
por: Nawaz, Muhammad, et al.
Publicado: (2018)

Ethanol Extract of Bupleurum falcatum Improves Functional Recovery by Inhibiting Matrix Metalloproteinases-2 and -9 Activation and Inflammation after Spinal Cord Injury
por: Lee, Jee Youn, et al.
Publicado: (2010)

Extra Cellular Matrix Remodeling: An Adjunctive Target for Spinal Cord Injury and Intervertebral Disc Degeneration
por: Kumar, Ashish, et al.
Publicado: (2022)

Cardiac fibroblasts, fibrosis and extracellular matrix remodeling in heart disease
por: Fan, Dong, et al.
Publicado: (2012)

Injectable Myocardial Matrix Hydrogel Mitigates Negative Left Ventricular Remodeling in a Chronic Myocardial Infarction Model
por: Diaz, Miranda D., et al.
Publicado: (2021)

Ameliorating Fibrotic Phenotypes of Keloid Dermal Fibroblasts through an Epidermal Growth Factor-Mediated Extracellular Matrix Remodeling
por: Kim, Hyunbum, et al.
Publicado: (2021)

Ex Vivo and In Vivo Properties of an Injectable Hydrogel Derived From Acellular Ear Cartilage Extracellular Matrix
por: Gong, Danni, et al.
Publicado: (2021)

Injectable exosome-functionalized extracellular matrix hydrogel for metabolism balance and pyroptosis regulation in intervertebral disc degeneration
por: Xing, Hongyuan, et al.
Publicado: (2021)

Nanoengineered hydrogels as 3D biomimetic extracellular matrix with injectable and sustained delivery capability for cartilage regeneration
por: Cui, Penglei, et al.
Publicado: (2022)

Improved rat spinal cord injury model using spinal cord compression by percutaneous method
por: Chung, Wook-Hun, et al.
Publicado: (2013)

Extracellular matrix remodelling properties of human fibrocytes
por: Bianchetti, Lorenza, et al.
Publicado: (2012)

Extracellular Matrix Remodeling During Palate Development
por: Wang, Xia, et al.
Publicado: (2020)

TRAIL signals, extracellular matrix and vessel remodelling
por: Patil, Manisha S, et al.
Publicado: (2020)

Extracellular Matrix Remodeling in Chronic Liver Disease
por: Ortiz, Cristina, et al.
Publicado: (2021)

Interdisciplinary Approaches to Spinal Cord Injuries: Innovations, Collaborations, and the Role of the Korean Spinal Cord Society and Korean Neurotraumatology Society
por: Oh, Hyuk Jin, et al.
Publicado: (2023)

Hydrogel-based treatments for spinal cord injuries
por: Jia, Zhiqiang, et al.
Publicado: (2023)

A bioactive injectable self-healing anti-inflammatory hydrogel with ultralong extracellular vesicles release synergistically enhances motor functional recovery of spinal cord injury
por: Wang, Chenggui, et al.
Publicado: (2021)

Genipin and EDC crosslinking of extracellular matrix hydrogel derived from human umbilical cord for neural tissue repair
por: Výborný, Karel, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_u6q7n30h4vo8f9ffkqqisqvj1q